TPP Triphenyl Phosphate

Triphenyl Phosphate TPP, TPHP, DPHP. SCA endorses products with the Toxic-Free Tick, that do not contain TPP and it's derivatives. TPP is flame retardent. Greater exposure to TPP is associated with altered hormone levels & lower sperm concentrations. The EPA ranks TPP as toxic to aquatic life such as fish.

CLASSIFICATION

CAS No: 603-35-0. TRIPHENYL PHOSPHATE; TPP and "Synonym(s): "PHOSPHORIC ACID, TRIPHENYL ESTER; TRIPHENYL ESTER PHOSPHORIC ACID; CELLUFLEX TPP; DISFLAMOLL TP; PHOSFLEX TPP; REOLUBE TPP; REOMOL TPP; TPP; TRIFENYLFOSFAT (CZECH) ; TRIPHENYL PHOSPHATE (ACGIH:OSHA)" - EWG

HOW IS IT USED:

Reported usage up to 1.6% TPP - Plasticiser used in nail polish and nail enamels, base coats and undercoats, and manicuring products. NICNAS reported commercial use in construction materials. Known skin sensitiser; "used in 372 leave-on manicuring preparations, with the majority of the uses being reported in nail polishes and enamels." - CIRSafety.org

RESEARCH - WHAT THE EXPERTS SAY

WHAT IS TRIPHENYL PHOSPHATE?

  • "The chemical has reported domestic and commercial use in paints, lacquers and varnishes." - NICNAS and, "Skin Irritation; The chemical is reported to slightly irritate the skin in animal studies. The irritation effects were not sufficient to warrant hazard classification." And, "Skin Sensitisation The chemical is considered to be a skin sensitiser based on positive results seen in a single guinea pig maximisation test (GPMT)"

  • "It is used as fire-retarding agent, and a plasticizer for cellulose acetate and nitrocellulose. Triphenyl phosphate also has been found as one component of lubricating oil and hydraulic fluids. HUMAN STUDIES: It causes a delayed peripheral neuritis involving motor neurons, resulting in a flaccid paralysis, particularly of the distal muscles." - ToxNet, And, "TPP caused generalized delayed illness and paralysis in cats and primates." And, "A case of triphenyl phosphate allergy from spectacle frames is reported." And, "results indicate that nail polish may be a significant source of short-term TPHP exposure and a source of chronic exposure for frequent users or those occupationally exposed." - ToxNet Peer Reviewed

RESOURCES & RECOMMENDED ARTICLES:

Amina Kitching