SCA endorses products with the Allergy Certified logo, that do not contain resorcinol. A study by the Toxicology Data Network found that “HUMAN EXPOSURE AND TOXICITY: An application of 3-25% solution of resorcinol to skin may cause redness, itching, dermatitis, edema or corrosion of affected area. Potential symptoms of overexposure are irritation of eyes, skin, nose, throat, upper respiratory system; dermatitis; methemoglobinemia, cyanosis, convulsions; restlessness, bluish skin, increased heart rate, dyspnea; dizziness, drowsiness, hypothermia, hemoglobinuria; spleen, kidney, liver changes.” -
CAS No: 108-46-3. Other Names: resorcinol; 1,3-dihydroxybenzene; 3-hydroxyphenol; 3-hydroxycyclohexadien-1-one; m-dihydroxybenzene
HOW IS IT USED?
It is used as an antiseptic and disinfectant in topical pharmaceutical products to treat skin problems, and infections, such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses and warts. And, as a colour additive, hair dye, specialty adhesive, in textiles, construction materials, and as a fragrance ingredient. NICNAS
RESEARCH - WHAT DO THE EXPERTS SAY?
TGA Poisons Standard Feb, 2019; except in hair dye, eyelash and eyebrow dye products (after mixing) containing 1.25% or less; label must state: KEEP OUT OF REACH OF CHILDREN, and "WARNING - "This product contains ingredients which may cause skin sensitisation to certain individuals. A preliminary test according to the accompanying directions should be made before use. This product must not be used for dyeing eyelashes or eyebrows; to do so may be injurious to the eye." And, "in hair lotions/shampoo products containing 0.5 per cent or less of resorcinol when the immediate container and primary pack are labelled with the following statement: WARNING – This product contains ingredients which may cause skin sensitisation to certain individuals" - TGA.
NICNAS advises that it is not restricted for use in Australian products; the EU Cosmetic Directive states: maximum concentration applied to hair must not exceed 1.25 % (w/w); and (b) Hair lotions and shampoos— maximum authorised concentration in the finished cosmetic product of 0.5 % (w/w).- NICNAS Chemical Information:
ASEAN Cosmetic Directive List of substances which cosmetic products must not contain except subject to restrictions.
New Zealand Cosmetic Products Group Cosmetics must not contain except subject to the restrictions and conditions laid down;
Health Canada List of prohibited and restricted cosmetic ingredients (The Cosmetic Ingredient ‘Hotlist’); and Chile list of Cosmetic Ingredients with limited use or concentration.
The chemical is classified as hazardous with the risk phrase 'Harmful if swallowed'
Safe Work Australia - 'Irritating to skin' and 'Irritating to eyes' (Xi; R36) in HSIS.
Repeated dose Toxicity: Human patch-testing using the chemical elicited allergic skin reactions in 0.7–0.8 % of 1694 dermatitis patients.
RESOURCES & RECOMMENDED ARTICLES:
"resorcinol, which can sometimes cause allergies and can be irritating." - Choice.com.au