Key Allergens Hotlist
“The ingredients responsible for allergy to cosmetics were determined in 119 patients suffering from cosmeticrelated contact dermatitis.
Most reactions (56.3%) were caused by skin care products, followed by nail cosmetics (13.4%), perfumes (8.4%), and hair cosmetics (5.9%).
Preservatives were most frequently implicated (32.0%), followed by fragrances (26.5%) and emulsifiers (14.3%).
By far the most important cosmetic allergen was Kathon CG, (a preservative system containing, as active ingredients, a mixture of methylisothiazolinone and methylchloroisothiazolinone) reacting in 33 patients (27.7%).
Other frequent causes of cosmetic-related contact allergic reactions were toluenesulfonamide/formaldehyde resin in nail hardener and/or nail lacquer (15 patients [12.6%]), and oleamidopropyl dimethylamine, an emulsifier in baby body lotion (13 patients [10.9%]). ( Arch Dermatol 1988;124:1525-1529)" - Scinapse.io/papers/2141505644