Iisothiazolinone & derivatives
Antimicrobial preservatives. SCA endorses products with the Allergy Certified logo inaccordance with international restrictions; 0.01% or less for leave-on and rinse-off products; less then 1% for cleaning products. Safety advice should be included for products containing isothiazoline derivatives - "not suitable for sensitive allergy prone skin" and, "not suitable for children under 3 years of age" and, "discontinue use if irritation occurs".
Large scale use of lisothiazolone accumulation & toxicity: “Isothiazolinone is widely used as a broad-spectrum fungicide in various industries, such as oil, paper, pesticide, dyes, tanning and cosmetics. There is an increasing concern over protection of the aquatic environment due to its large-scale use. Temperature affected accumulation and toxicity of isothiazolinone.” - www.sciencedirect.com
CAS No: 26172-54-3 & CAS No: 26172-55-4
WHAT IS IT?
Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT; "are two of the most predominant contact allergens found in cosmetic products. The American Contact Dermatitis Society named MIT Allergen of the Year for 2013 due to the skin sensitization resulting from dermal exposure to it." - SafeCosmetics.org
3-Isothiazolone: commonly known as Kathon preservative; found in baby products, shampoos, soaps, detergents, bubble baths, lotions, oils, powders, creams, makeup and remover, fragrances, face powders, hair products and dyes, deodorant, after shave and shaving products, hand and body creams, masks, ltions, suntan gels and self tanners.
HOW IS IT USED?
"Methylisothiazolinone (MI) is a preservative used in baby wipes and other personal products, which is currently causing an appreciable number of cases of allergic contact dermatitis, an itchy skin rash. Preservatives like MI are needed in moist wipes to prevent bacterial contamination." - occderm.asn.au (and biocide; a poisonous substance)
RESEARCH - WHAT THE EXPERTS SAY:
European SCCS; Known human immune toxicant or allergen; Violation of government restrictions - Banned or found unsafe for use in cosmetics.
GermanBfr; Violation of government restrictions - Banned or found unsafe for use in cosmetics.
Canada; restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics.
Japan; Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions.
Cosmetic Ingredient Review; Human skin toxicant or allergen - strong evidence.